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Genome Engineering with CRISPR & Cas Workshop

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Presenters:  Thomas Tubon, PhD, Madison College, Sandra Porter, PhD, Digital World Biology and Bio-Link

Together CRISPR and Cas provide bacteria with an adaptive immune system that allows them to identify and defend against new viral invaders. While characterizing the basic biology of this system, researchers discovered that the Cas9 protein could be harnessed to engineer genomic DNA. In this session, we will discuss the basic biology of the CRISPR / Cas system and discuss how researchers are using this system in new ways to engineer living things.

We also explored molecular models of Cas proteins bound to CRISPR RNA and DNA with Molecule World on the iPad. A collection of these structures can be found in the CRISPR Structure Collection from Digital World Biology.