biomanufacturing

Speaker : Bruce Van Dyke, Quincy College, MA

Host : Dr. Sandra Porter, Digital World Biology, InnovATE BIO .org

1. Watch Webinar1: Virtual Single-use Biomanufacturing

2. Visit the Virtual Single-Use Biomanufacturing on-line module password : qcbtc

3. Go to the bottom of the page to download the handouts

A QUICK TOUR

As described in on the event page , the Biosciences Industry Fellowship Program, hosted by Forsyth Technical Community College in Winston-Salem North Carolina, was an action packed three weeks. The first week included visits and workshops in partnering schools. During the second week we participated in a week long green fluorescent protein biomanufactuing workshop that covered the gamut from 30 liter fermentation, to isolation, to purification, to filling vials in sterile conditions. In the last week we visited and toured area biotechnology companies and closed with presentations by the participants.

Photos from the workshop are below.

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The utilization of single use technologies for some or all of the processes in biotechnology have become common. Engineers can substitute plastic components for stainless steel-permanently plumbed systems at any point in the biomanufacturing process, although the technology to do this in the upstream process is much more mature than in downstream technologies. This approach replaces reusable stainless steel equipment with disposable, typically plastic, components.

The industry often uses the terms “single-use” and “disposable” as synonyms. In the early days of this technology vendors emphasized the term single use because it sounded better – the situation was similar to... Read more

Many of the drugs and other products that biotechnology companies produce are based on monoclonal antibodies. Biotechnicians who know how to work with and purify these materials are in demand.

Recently, the Northeastern Biomanufacturing Center and Collaborative (NBC2) made new curriculum modules available that include procedures for the upstream and downstream methods used to produce a specific anti-IL8 monoclonal antibody from CHO cells. This work was funded by a grant from the National Science Foundation’s Advanced Technology Education program (DUE #1501631).

Since antibodies play such a critical role in biotechnology, I thought it would good to... Read more