COVID-19

By: 
Linnea Fletcher
Yellow viral particles bound to blue cilia
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By: 
EA Stewart
SAR-CoV-2 illustration: credit CDC
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This video shows how to:

1. Make a genome dataset and prepare a phylogenetic tree with viral genomes
2. Make a protein dataset and create a multiple alignment with sequences from spike proteins
3. Look at viral evolution in NextStrain.org
4. See where the D614G mutation ... View video

Filed under: COVID-19SARS-CoV-2

We discuss four kinds of projects that students can do to learn about molecular interactions between the novel SARS coronavirus and the cells it infects.

1. We use iCn3D to look at the SARS-CoV-2 spike protein in closed and open conformations.
2. We search for the human ACE2 gene ... View video

Filed under: iCn3DbioinformaticsCOVID-19NCBIClinVarGene databaseACE2SARS-CoV-2High school biotech

This talk was presented by Dr. David Koelle, a guest speaker from the University of Washington, Center for Innate Immunity and Immune Disease.  Dr. Koelle studies virology and immunology, along with viral oncogenesis, tumor immunotherapy, practical vaccinology issues such as adjuvants and ... View video

Filed under: COVID-19IAB webinarvaccinesimmunology
Fri, Jun 5 2020
An antigen presenting cell presents a peptide antigen to a T cell

This Friday, we will have a guest speaker from the University of Washington, Center for Innate Immunity and Immune Disease, share basic concepts around vaccines. This lecture will help us prepare for a later discussion when we dive into vaccines against COVID-19 in greater detail.

Speaker : Dr. David Koelle , Center for Innate Immunity and Immune Disease, University of Washington.
Dr. Koelle studies virology and immunology, along with viral oncogenesis, tumor immunotherapy, practical vaccinology issues such as adjuvants and delivery systems ... Read more

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Dr. Sandra Porter demonstrates how the Immune Epitope Database (IEDB.org) can be used for online research projects and provides an example of using this resource to investigate immunity to SARS-CoV-2 and SARS.

Speakers

Filed under: COVID-19IAB webinarantibodiesbioinformaticsimmunology

Dr. Lisa Seidman from Madison College discusses antibody assays for COVID-19 and illustrates how diagnostic sensitivity and specificity can be used together with prevalence to predict the number of false positive, true positive, false negative, and true negative results. Dr. Seidman also ... View video

Filed under: IAB webinarantibodiesDiagnosticsCOVID-19

What's it like to scale your testing capacity from 30 tests a week to 3000 a day?  Dr. Meei-Li Huang from the Virology division at the University of Washington tells us what it was it like to work on the front line of the COVID-19 pandemic, evaluating quantitative RT-PCR assays and testing  ... View video

Filed under: online researchbioinformaticsCOVID-19IAB webinarmolecular diagnosticsquantitative RT-PCR
Posted from Discovering Biology in a Digital World by Todd Smith on Wed May 13, 2020
Types and kinds of SARS-CoV-2 molecular diagnostics

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